Ectoine (synthetic)


Technical name: (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 
CAS No: 96702-03-3
Empirical formula: C6H10N2O2
Molecular weight: 142.16


Ectoine is a natural, highly-soluble, low-molecular-weight, zwitterionic cyclic amino acid derivative, found in several species of extremophilic microorganisms. It is a compatible solute, also called extremolyte, which serves to stabilize the physiological properties of the cells and  protect them from external osmotic stress, caused by high salinity, heat, loss of water and UV irradiation. 

Ectoine exerts cell-protective, anti-inflammatory and anti-allergic activity, and demonstrates a high efficacy and safety profile.



  • Prevention of stress mediators
  • Natural protection of cells
  • Lubrication and hydration effect
  • Anti-inflammatory activity
  • Anti-allergic activity


We offer high quality synthetic Ectoine, ≥98% (HPLC).

Low biological burden

Contrary to fermentation, our synthetic ectoine has low biological burden, which makes it, readily suitable for all applications.

Cost effective high volume production

We have developed and optimized our chemical process in-house for safe, lean and scalable cGMP manufacturing, providing significant economic benefits for high volume production.  



Ectoine has commercial uses as an enzyme stabilizer and as a cell protectant in skin and health care applications.

In dermatology, it is often contained in cream preparations for the treatment of skin dryness, roughness and scaliness (atopic dermatitis, psoriasis), UV-induced sunburn cells and overall skin dehydration.

Thanks to its lubricating effect, ectoine is also administered for the treatment of eye disorders. It relieves irritation and inflammation by stabilizing the watery layer and the lipid layer of the tear film, thus ensuring optimal protection.

Ectoine is also used in nasal sprays to treat symptoms of respiratory impairment, induced by carbon-related lung inflammation, allergic rhinitis or asthma.


Chemical structure for ectoine

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